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AudiologyNOW: A Wide Range of Educational Offerings Wednesdays Learning Labs are half-day (choice of four topics) or full-day (choice of three topics) sessions tailored to provide in-depth education on cutting-edge clinical techniques and winning practice-management tools. There are many educational opportunities offered Thursday through Saturday. The Symposia are topics of special interest presented by experts who are invited to speak for an extended period of time. Three symposium topics are planned for this year: Stem Cell Research (Jeffrey Kahn and Allen Ryan), Gene Therapy (Yehoash Raphael and Chester Whitley), and Electrophysiologic Evaluation of Infants (David Stapells, Barbara Cone-Wesson, and Terence Picton). NOW!Sessions are presented by top audiologists, hearing scientists, and physicians who will speak on current topics based upon their area of expertise. The Learning Modules are courses on topics of current interest incorporating interactive learning styles. These are one-hour (introductory/ overview) or two-hour (advanced/in-depth) sessions on topics of current interest to attendees. Similarly, Exhibitor Courses focus on clinical research presented by exhibitors that illustrate product performance, benefit, and/or satisfaction. Two types of discussion groups are offered: Discussion Sessions with facilitators on topics of current interest, and Focus Groups that feature an invited facilitator with a focused agenda. Research Pods are composed of four 15-minute research presentations on a related topic. The convention will also feature Research Poster Presentations (noon Thursday to noon Saturday, with a Poster Reception held Friday from 5 pm6:30 pm). Attending AAA 2006
AAS Preview: Scientific Research Meets Clinical Experience The efforts of AAS to encourage translational, clinical, and interdisciplinary research have been fostered by a National Institutes of Health (NIH) Conference grant, which has provided support for translational research lectures, special sessions, and student/resident research presentations over the past 5 years. Unique is the AAS meeting design that offers a forum in which basic scientists present their research to a clinically oriented audience, with the intention of increasing the practical value of their research. The following is a preview of only a few of this years presentations. (Editors Note: Information and photos in this article were made available to HR by Wayne J. Staab, PhD, executive director of AAS). 2006 Carhart Memorial Lecture
Translational Research Lectures Ascertaining Benefit of Bilateral Implantation in Children and Adults. Presented by Ruth Litovsky, PhD, Waisman Center, University of Wisconsin-Madison, Madison, Wis. In the intact auditory system, sounds from the two ears merge in the brainstem, forming an elaborate and precise set of cues that are known to be important for our ability to function in realistic, complex acoustic environments. This includes sound localization and speech understanding in noisy environments. The research discussed by Litovsky is aimed at understanding the circumstances under which bilateral implantation might be beneficial and the age at which such a benefit can be reliably ascertained. Litovskys translational research lecture will describe testing paradigms and ideal stimulus parameters that are believed to have potential use for achieving these goals. Measures that are appropriate for young children, as well as for adults will be presented, along with pilot data from a subset of patients. For children, tests engage the listeners in a hearing game. Speech reception thresholds (SRT) are obtained in quiet and in the presence of competing sounds that are either spatially coincident with or separated from the target speech. Sound localization precision is measured in the form of source location identification and location discrimination (with and without echoes). For bilaterally implanted individuals, the most beneficial scenarios are potentially more complex, given the lack of acute binaural information. Thus, proving bilateral benefit is a fairly complex challenge. Hair Cell Regeneration and Stem Cell Transplantation in the Cochlea. Presented by Doug Cotanche, PhD, Childrens Hospital, Department of Otolaryngology, Boston. Almost 20 years ago it was first demonstrated that birds are able to regenerate their cochlear hair cells following noise damage or aminoglycoside treatment. Since that initial discovery, Cotanches lab and labs of other colleagues have been working to understand the underlying cellular, molecular, and genetic mechanisms that control hair cell regeneration in birds.
The goal in these studies is to apply what we have learned about regeneration in birds to develop potential therapeutic approaches to hearing loss in the mammalian (and, eventually, the human) inner ear. This AAS translational research lecture will review the mechanisms of hair cell regeneration in the avian cochlea and how the cell cycle and cell death are fundamental to hair cell regeneration. It will also address current experiments on genetic manipulations of the mammalian inner ear, gene therapy approaches to induce new hair cell differentiation, and the potential of stem cell transplantation to replace lost or damaged cochlear cells. It is hoped that future discoveries in one or all of these approaches will provide an impetus for developing hair cell regeneration as a therapeutic tool for hearing loss in mammals. Measurements of Middle-Ear Function in Live Human Ears in Normal and Pathologic Conditions Using Laser-Doppler Vibrometry. Presented by John J. Rosowski, PhD, Massachusetts Eye and Ear Infirmary, Eaton-Peabody Laboratory and Harvard Medical School, Boston. The third translational research lecture will describe the work of scientists who use a laser to determine the sound-induced velocity of the tympanic membrane (TM) in normal and pathological ears. A sample of ears from over 60 individuals with normal hearing demonstrate wide variations in sound-induced TM velocity (±10 dB)a fact that complicates the utility of TM velocity in diagnosis. In a population of ears with sensorineural hearing loss, but no air-bone gaps, the researchers found no correlation between hearing threshold and the measured velocity, suggesting that the micro-mechanics of the inner ear have little effect on TM velocity. In the same population, they also saw little evidence for age-related changes in middle-ear function. The researchers have also investigated conductive hearing loss with an intact TM. While results demonstrate that laser vibrometry by itself is an insensitive measure of conductive loss, the combination of vibrometry and audiometric testing can be used to reliably differentiate stapes fixation from ossicular interruption. Researchers are also able to differentiate patients with superior-canal dehiscence from stapes fixation, two conditions that cause similar hearing loss. Finally, laser vibrometry is being used as a research tool in the operating room to investigate sound-induced stapes velocity in patients with normal middle ears who are undergoing cochlear implantation. Hearing Aid Algorithms. Presented by Steve Armstrong, BSEE, Senior Design Architect, Hearing Instruments Division, Gennum Corp, Burlington, Ontario. With the advent of digital signal processing (DSP) in hearing aids, algorithms and their development have taken an advanced role in the enhancement of amplified signals. This AAS translational research lecture will identify salient characteristics and approaches used in algorithms to enhance the signal for hearing-impaired individuals, as well as to identify those not yet fully applicable. Some of these relate to concepts and approaches to be discussed in the Special Session that follows the presentation (see Special Session: Hearing Aid Developments). The intent of Armstrongs lecture is to introduce engineering concepts and projections to practical uses of such algorithms, and to relate these results to sound quality and fidelity considerations. Practical considerations of electronic progress will be discussed, including current/power implications, open platform systems, bandwidth, dynamic range, phase and open fittings, power digital aids, and multiband trade-offs. For example, gain adjustments result in a multitude of signal processing distortions, depending on the manner in which the gain adjustments are made. Additionally, future directions of digital listening devices for the hearing impaired will be presented. Special Session: Hearing Aid Developments
Noise Reduction and Other Automatic Features. Presented by Ruth Bentler, PhD, University of Iowa, Iowa City, Iowa. Sound classificationor sound-scene analysis, as the term is used in hearing aid algorithm designis intended to alter the signal processing scheme across different listening environments. Although the rules of the algorithms vary from manufacturer to manufacturer, the obvious goal is for the amplification algorithm to correctly identify those noises that interfere with communication and reduce or eliminate their impact. In her presentation, Bentler will provide an overview of some of the automatic systems available, along with data from a large-scale project (randomized control trial) addressing the effectiveness of noise reduction in hearing aids for mild-to-moderate hearing loss subjects. Feedback Cancellation in Hearing Aids. Presented by James Kates, PhD, GN ReSound, Chicago. Feedback presents a serious problem in hearing aids, often limiting the maximum gain that can be provided by the instrument. Kates presentation will review the causes of acoustic and mechanical feedback in hearing aids and the effects of feedback on the system behavior. Techniques for reducing feedback will be described, with an emphasis on systems that cancel feedback by modeling the feedback path and subtracting the estimated feedback signal from the hearing-aid input. Feedback cancellation effectiveness and limitations on system performance, including problems caused by sinusoidal inputs and room reverberation, will also be discussed.
Special Session: Introduction to NIH Research Daniel Sklare, PhD, will also head an NIH research forum during the conference. With NIH support, the meeting also provides travel to students and residents engaged in research, enabling them to present their work to an audience that includes both basic and clinical research scientists. How To Attend
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