Search Results for: age-related hearing loss

Research Shows Hair Cell Damage May Be Main Cause of Age-related Hearing Loss

Researchers examined 120 inner ears collected at autopsy. They used multivariable statistical regression to compare data on the survival of hair cells, nerve fibers, and the stria vascularis with the patients’ audiograms to uncover the main predictor of the hearing loss in this aging population. They found that the degree and location of hair cell death predicted the severity and pattern of the hearing loss, while stria vascularis damage did not.

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Age-related Hearing Loss Genes Discovered in Fruit Flies

“Our twin discoveries that fruit flies experience age-related hearing loss and that their prior auditory health is controlled by a particular set of genes, is a significant breakthrough. The fact that these genes are conserved in humans will also help to focus future clinical research in humans and thereby accelerate the discovery of novel pharmacological or gene-therapeutic strategies,” says lead-author Joerg Albert.

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Creighton University Researcher Receives $1.9 Million Grant to Study Age-related Hearing Loss

Much of Dr He’s research will focus on inner and outer hair cells, the two types of receptor cells that convert sound into electrical impulses in the auditory nerve. He will compare the changes at the cellular and molecular levels of hair cells between young and aging mice to determine age-related changes in gene expression, ultrastructure, and cellular function.

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