Researchers examined 120 inner ears collected at autopsy. They used multivariable statistical regression to compare data on the survival of hair cells, nerve fibers, and the stria vascularis with the patients' audiograms to uncover the main predictor of the hearing loss in this aging population. They found that the degree and location of hair cell death predicted the severity and pattern of the hearing loss, while stria vascularis damage did not.
Auris Medical will develop betahistine dihydrochloride in a spray formulation for the intranasal treatment of Ménière’s disease and vestibular vertigo. The company also announced last week that it has resumed patient enrollment in the TACTT3 Phase 3 trial of Keyzilen® (AM-101) for acute and post-acute inner ear tinnitus.
A new report from Hearing Review, sponsored by Hamilton® CapTel®, reviews the demographics and special audiological considerations hearing care professionals should keep in mind when treating this important patient population.
In the future, scientists may be able to use the data to steer stem cells toward the hair cell lineage, helping to produce the specialized cells they need to test cell replacement approaches for reversing some forms of hearing loss.
Researchers looked at mice engineered to have progressive hearing loss, and found that their neurotransmitter receptors—responsible for communication between brain cells—exhibited changes in sensory processing regions related to memory.
The Ancient and Honorable Artillery Company of Massachusetts—a chartered military organization—settled a lawsuit with a man who alleged that he now has permanent hearing loss and tinnitus after attending a group event where howitzers were fired.